gapo syndrome造句

• Due to the severity of the phenotype, GAPO syndrome can be diagnosed very early on.
• As a result, individuals with GAPO syndrome have a buildup of extracellular matrix, and degraded cell adhesions.
• GAPO syndrome is inherited in an autosomal recessive fashion, and requires both parents to pass on the mutant genotype.
• GAPO syndrome is caused by a deletion in both copies of the ANTXR1 gene, which encodes Anthrax Toxin Receptor 1.
• No direct correlation has been found between GAPO syndrome and mental retardation, though cases of individuals having both have been reported.
• "' GAPO syndrome "'is a rare, autosomal recessive disorder that causes severe growth retardation, and has been observed fewer than 30 times before 2011.
• While not a defining feature, most sufferers of GAPO syndrome have coarse facial features, and abnormal structure of the middle portion of their faces, typically coupled with a large forehead.